Natan Pernick was born in 1980, in Israel.

Pernick  is an Israeli painter who started painting at the age of 14, when he also practiced mural painting. Between 2002-2004 Pernick  lived and worked in New York as an apprentice at the studio of the renowned artist Mark Kostabi. In 2004-2008, Pernick attended the department of Visual Communications at the Bezalel Academy of the Arts and Design. During his studies, he began showing his work at various art galleries in Jerusalem. In 2009, Pernick participated at the Artishock – young art initiative, as well as partook at a group exhibition at the National Portrait Gallery in London for the BP portrait award.